David A Calhoun Selected Research

Spironolactone (Aldactone)

1/2021	Spironolactone Reduces Aortic Stiffness in Patients With Resistant Hypertension Independent of Blood Pressure Change.
1/2019	Plasma xanthine oxidase activity is related to increased sodium and left ventricular hypertrophy in resistant hypertension.
11/2018	Resistant Hypertension: Detection, Evaluation, and Management: A Scientific Statement From the American Heart Association.
2/2017	Use of Aldosterone Antagonists for Treatment of Uncontrolled Resistant Hypertension.
1/2017	Refractory versus resistant hypertension.
1/2017	White-Coat Effect Is Uncommon in Patients With Refractory Hypertension.
1/2017	Effects of Spironolactone and Renal Denervation Treatment on Blood Pressure and Its Variability-Different Aspects of Hypertension Treatment.
5/2016	Urinary sodium excretion predicts blood pressure response to spironolactone in patients with resistant hypertension independent of aldosterone status.
1/2016	Spironolactone versus renal nerve denervation for treatment of uncontrolled resistant hypertension.
10/2013	Management of patients with resistant hypertension: current treatment options.

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David A Calhoun Research Topics

Disease

115	Hypertension (High Blood Pressure) 01/2022 - 12/2002
27	Hyperaldosteronism (Conn Syndrome) 01/2020 - 12/2002
11	Obstructive Sleep Apnea 01/2019 - 03/2004
10	Chronic Renal Insufficiency 01/2021 - 01/2007
10	Obesity 01/2018 - 03/2004
9	Stroke (Strokes) 07/2015 - 04/2011
8	Heart Failure 01/2022 - 06/2005
8	Cardiovascular Diseases (Cardiovascular Disease) 01/2020 - 08/2002
8	Myocardial Infarction 04/2017 - 06/2003
7	Sleep Apnea Syndromes (Sleep Apnea) 01/2018 - 01/2004
6	Hyperkalemia 05/2012 - 05/2006
4	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 01/2019 - 05/2010
4	Essential Hypertension 01/2013 - 09/2011
3	Inflammation (Inflammations) 01/2016 - 02/2009
3	Isolated Systolic Hypertension 03/2014 - 11/2009
3	Hypokalemia 05/2012 - 06/2005
3	Weight Loss (Weight Reduction) 11/2009 - 03/2006
3	Adenoma (Adenomas) 03/2009 - 11/2005
2	Hypoxia (Hypoxemia) 01/2019 - 02/2012
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2018 - 02/2009
2	Coronary Disease (Coronary Heart Disease) 11/2014 - 10/2013
2	Type 2 Diabetes Mellitus (MODY) 10/2014 - 10/2014
1	Gout 01/2021
1	Pre-Eclampsia (Preeclampsia) 01/2021
1	Hypertrophy 01/2019
1	Abdominal Obesity 10/2016
1	Hyperuricemia 01/2016
1	Chronic Kidney Failure (Chronic Renal Failure) 11/2014
1	Peripheral Arterial Disease 11/2014
1	White Coat Hypertension 10/2014
1	Diabetes Mellitus 10/2013

Drug/Important Bio-Agent (IBA)

69	Antihypertensive Agents (Antihypertensives)IBA 01/2020 - 08/2002
50	AldosteroneIBA 01/2021 - 12/2002
30	DiureticsIBA 01/2020 - 11/2003
27	Mineralocorticoid Receptor AntagonistsIBA 01/2021 - 03/2004
23	ReninIBA 01/2020 - 12/2002
19	Spironolactone (Aldactone)FDA LinkGeneric 01/2021 - 12/2002
18	SodiumIBA 01/2022 - 12/2002
12	SaltsIBA 01/2021 - 12/2002
11	Chlorthalidone (Chlortalidone)FDA LinkGeneric 01/2020 - 01/2007
10	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2019 - 11/2003
9	ThiazidesIBA 01/2020 - 09/2011
9	Hydrochlorothiazide (Esidrix)FDA LinkGeneric 08/2013 - 06/2005
8	Angiotensin Receptor AntagonistsIBA 01/2019 - 11/2003
7	Dietary SodiumIBA 01/2019 - 02/2008
6	Sodium Chloride Symporter Inhibitors (Diuretics, Thiazide)IBA 09/2016 - 11/2008
6	PotassiumIBA 09/2014 - 11/2007
5	Calcium Channel Blockers (Blockers, Calcium Channel)IBA 01/2019 - 10/2013
5	Eplerenone (Inspra)FDA LinkGeneric 11/2018 - 06/2005
5	Amlodipine (Norvasc)FDA LinkGeneric 04/2017 - 07/2009
5	LipidsIBA 04/2017 - 10/2005
4	Pharmaceutical PreparationsIBA 01/2019 - 11/2009
4	Valsartan (Vals)FDA Link 08/2013 - 06/2008
3	Drug CombinationsIBA 01/2019 - 06/2008
3	AngiotensinsIBA 01/2019 - 06/2005
3	Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA 01/2018 - 05/2010
3	Lisinopril (Prinivil)FDA LinkGeneric 04/2017 - 05/2012
3	Amiloride (Midamor)FDA LinkGeneric 01/2014 - 05/2006
3	CreatinineIBA 09/2013 - 06/2003
2	Xanthine OxidaseIBA 01/2022 - 01/2019
2	Mitochondrial DNA (mtDNA)IBA 01/2022 - 11/2017
2	Uric Acid (Urate)IBA 01/2021 - 01/2016
2	Hydrocortisone (Cortisol)FDA LinkGeneric 05/2017 - 06/2008
2	Brain Natriuretic Peptide (Natrecor)FDA Link 09/2016 - 05/2010
2	Triamterene (Dyrenium)FDA LinkGeneric 01/2016 - 09/2011
2	Sodium Potassium Chloride Symporter Inhibitors (Loop Diuretics)IBA 10/2014 - 09/2011
2	Valsartan Drug Combination Amlodipine FDA Link 08/2013 - 11/2009
2	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 06/2005 - 11/2003
1	GlycogenIBA 01/2022
1	CatecholaminesIBA 01/2021
1	Biomarkers (Surrogate Marker)IBA 01/2021
1	Reserpine (Serpasil)FDA Link 01/2020
1	Oxyhemoglobins (Oxyhemoglobin)IBA 01/2019
1	Indapamide FDA LinkGeneric 11/2018
1	Cortisone FDA Link 05/2017
1	Oxidoreductases (Dehydrogenase)IBA 05/2017
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 09/2016
1	SympatholyticsIBA 07/2015
1	NormetanephrineIBA 07/2015
1	Dipyridamole (Persantine)FDA LinkGeneric 02/2015
1	Hypoglycemic Agents (Hypoglycemics)IBA 10/2014
1	salicylhydroxamic acid (SHAM)IBA 10/2014
1	Glucagon-Like Peptide-1 ReceptorIBA 10/2014
1	dulaglutideIBA 10/2014
1	Glucagon-Like Peptide-1 Receptor AgonistsIBA 10/2014
1	N 30IBA 03/2014
1	Sodium Channels (Sodium Channel)IBA 01/2014
1	ORALIT (ORS)IBA 10/2013
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 09/2013
1	AlbuminsIBA 09/2013
1	erucylphosphocholineIBA 09/2013
1	CytokinesIBA 09/2013
1	IsoprostanesIBA 02/2012
1	hydroxide ionIBA 01/2012

Therapy/Procedure

27	Therapeutics 01/2021 - 08/2002
4	Denervation 01/2017 - 01/2012
3	Ambulatory Care (Outpatient Care) 01/2020 - 04/2017
2	Drug Therapy (Chemotherapy) 10/2014 - 10/2013
2	Dietary Approaches To Stop Hypertension 09/2014 - 02/2013
1	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 01/2018